Psoriasis Causes

Psoriasis Causes

It is now clear that psoriasis has a genetic basis. This genetic predisposition is necessary before the disease can be triggered by environmental factors. Called T cells of leukocytes mediate the development of psoriasis plaques present in the skin. When someone suffers from psoriasis, their body can not provide the intruder's protection. In contrast, inflammation is promoted and skin cells are over-driven. When cell growth increases, the old skin cells accumulate rather than peeling, resulting in psoriasis. At present, most experts believe that environmental, genetic and immune factors interact with the disease.

Psoriasis trigger

If you have a genetic basis for psoriasis, triggers can cause psoriasis. The following are possible triggering factors that may cause psoriasis:

Streptococcus (a sore throat)

The skin of the trauma (cut, scraping, insect bites, infection, sunburn)

Certain drugs (lithium, hypertension and heart drugs, beta-blockers, antimalarials, indomethacin)

HIV

Stress

Obesity

Is psoriasis infected?

No, psoriasis is not contagious. People used to think that psoriasis was the same as leprosy, but that was not the case. You can not get psoriasis from touching, kissing or having sex with people suffering from psoriasis. People get psoriasis because of their genes, not their hygiene, diet, lifestyle, or any other habit.

Diagnosis of psoriasis

Psoriasis is usually diagnosed or at least suspected according to its appearance and distribution. However, psoriasis may be similar to eczema or other skin diseases that may require further testing. It may be necessary to remove a small piece of skin (biopsy) and check by the pathologist to confirm the diagnosis. If there are joint symptoms, X-rays and other laboratory tests may be orderly. Psoriasis can not be cured, but like many other medical conditions, it is controllable treatment. Your doctor may be consulted by a dermatologist, rheumatologist or immunologist to help diagnose and treat your psoriasis form.

Psoriasis treatment: local medicine

Since psoriasis affects the skin primarily, topical treatment is very useful because they are relatively safe, quite effective, and can be applied directly to the affected skin. They are in the form of lotions, foams, creams, ointments, gels, and shampoos. They include topical steroids, tar preparations, and calcium medications. The precise use of drugs and their delivery depends on the scope of the exposure. In patients with more than 10% of the body's surface, the prevalence of disease, the use of local administration alone may not be practical.

Psoriasis treatment: light therapy

For a wider range of psoriasis, a useful option is ultraviolet (UV) light. If carried out in the doctor's office, UV light can treat large areas of the skin, almost no side effects. It should be remembered that all the UV light can cause mutations that may cause skin cancer. At this point, the most popular UV light type for psoriasis is called narrowband UVB. Using only a small portion of the UV spectrum, which seems to be particularly beneficial for psoriasis and may not be carcinogenic. This UVB is completely different from the UVA at the wavelength available in tanning salons, which is ineffective in psoriasis. In the treatment of psoriasis, light therapy can be used alone or in conjunction with drugs.

Psoriasis treatment: laser treatment

Excimer lasers or pulsed dye lasers for laser treatment. The pulsed dye laser will produce a bundle of yellow beams. When this light strikes the skin, it turns into heat. Then, heat will destroy the extra blood vessels that contribute to psoriasis in the skin. The excimer laser will provide UV rays to the local area of the skin, helping to treat psoriasis. These lasers produce wavelengths similar to narrowband UVB's ultraviolet light. Laser treatment uses a lot of lasers to help control the mild to moderate psoriasis area without damaging the surrounding healthy skin. These small plaques for psoriasis may be quite effective, but because they can only treat small areas of skin at once, they are not practical for a wide range of diseases.

Psoriasis Treatment: Oral Medication

Drugs of a variety of medicines used to treat psoriasis are, as a generalization, most oral medicines play a role in targeting the immune system. It's the only exception is a drug called Soriatane, which is structurally similar to vitamin A. As the immune system is essential, to avoid, systematic treatment is actually a disadvantage. Drugs such as methotrexate and cyclosporin oral administration can affect the liver, kidney, bone marrow. Recently approved new oral medication for the treatment of psoriasis is called Ota Sela (apremilast). Stella targets selective molecules in immune cells and controls the intracellular inflammatory process (reduces), which in turn is recommended for psoriasis The drug contributes to the treatment is quite safe, and most of its predecessors are quite expensive.

Psoriasis Treatment: Biology

Recently a new class of biological sciences has been developed; They are called biology because living cells synthesize them. Since these drugs are proteins, they can not be administered verbally and should be given by injection through the skin or inhalation infusion. This treatment is recommended in patients with moderately severe psoriasis, these drugs target the immune response, which gives rise to acute skin cell growth of psoriasis. It seems that their safety profile, as well as their effectiveness, increased compared to older medicines. On the other hand, they are spending $ 30,000 a year at an expensive cost.